Alcohol: It is unsafe to consume alcohol with Pardifen 650mg Tablet. Pregnancy: Pardifen 650mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Breastfeeding: Pardifen 650mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Driving: Pardifen 650mg Tablet does not usually affect your ability to drive. Kidney: Pardifen 650mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pardifen 650mg Tablet may be needed. Please consult your doctor.However, Pardifen 650mg Tablet contains paracetamol which is considered the safest painkiller for kidney disease patients. Liver: Pardifen 650mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pardifen 650mg Tablet may be needed. Please consult your doctor.However, the use of Pardifen 650mg Tablet is not recommended in patients with severe liver disease and active liver disease.