Alcohol: Febrex 125mg/5ml Syrup should be used with caution in patients with severe kidney disease. Dose adjustment of Febrex 125mg/5ml Syrup may be needed. Please consult your doctor.However, Febrex 125mg/5ml Syrup contains paracetamol which is considered the safest painkiller for children with kidney disease. Pregnancy: Febrex 125mg/5ml Syrup should be used with caution in patients with liver disease. Dose adjustment of Febrex 125mg/5ml Syrup may be needed. Please consult your doctor.However, the use of Febrex 125mg/5ml Syrup is not recommended in children with severe liver disease and active liver disease.