Alcohol: It is unsafe to consume alcohol with Apendol 50mg Tablet DT. Pregnancy: Apendol 50mg Tablet DT may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Breastfeeding: Apendol 50mg Tablet DT is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Driving: Apendol 50mg Tablet DT may cause side effects which could affect your ability to drive.If you feel drowsy, dizzy, have blurred vision or a slow reaction time while taking Apendol 50mg Tablet DT, then do not drive. Kidney: Apendol 50mg Tablet DT should be used with caution in patients with kidney disease. Dose adjustment of Apendol 50mg Tablet DT may be needed. Please consult your doctor. Liver: Apendol 50mg Tablet DT should be used with caution in patients with severe liver disease. Dose adjustment of Apendol 50mg Tablet DT may be needed. Please consult your doctor.Use of Apendol 50mg Tablet DT is not recommended in patients with severe kidney disease.