Alcohol: Cofrelax LS Syrup may cause excessive drowsiness with alcohol. Pregnancy: Cofrelax LS Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Breastfeeding: Cofrelax LS Syrup is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Driving: Cofrelax LS Syrup may cause side effects which could affect your ability to drive. Kidney: Cofrelax LS Syrup should be used with caution in patients with kidney disease. Dose adjustment of Cofrelax LS Syrup may be needed. Please consult your doctor.Limited information is available on the use of Cofrelax LS Syrup in these patients. Liver: Cofrelax LS Syrup should be used with caution in patients with liver disease. Dose adjustment of Cofrelax LS Syrup may be needed. Please consult your doctor.Limited information is available on the use of Cofrelax LS Syrup in these patients.