Alcohol: Xoloril Syrup may cause excessive drowsiness with alcohol. Pregnancy: Xoloril Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Breastfeeding: Xoloril Syrup is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Driving: Xoloril Syrup may cause side effects which could affect your ability to drive. Kidney: Xoloril Syrup should be used with caution in patients with kidney disease. Dose adjustment of Xoloril Syrup may be needed. Please consult your doctor.Limited information is available on the use of Xoloril Syrup in these patients. Liver: Xoloril Syrup should be used with caution in patients with liver disease. Dose adjustment of Xoloril Syrup may be needed. Please consult your doctor.Limited information is available on the use of Xoloril Syrup in these patients.