Alcohol: Prozimol Syrup is safe to use in patients with kidney disease. No dose adjustment of Prozimol Syrup is recommended.However, caution is advised in patients with severe kidney disease as it may cause excessive sleepiness in them. Pregnancy: Prozimol Syrup should be used with caution in patients with liver disease. Dose adjustment of Prozimol Syrup may be needed. Please consult your doctor.The use of Prozimol Syrup is not recommended in children with severe liver disease and active liver disease.