Alcohol: It is unsafe to consume alcohol with Doltrax MR 50mg/325mg/250mg Tablet. Pregnancy: Doltrax MR 50mg/325mg/250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. Breastfeeding: Information regarding the use of Doltrax MR 50mg/325mg/250mg Tablet during breastfeeding is not available. Please consult your doctor. Driving: Doltrax MR 50mg/325mg/250mg Tablet may cause side effects which could affect your ability to drive. Kidney: Doltrax MR 50mg/325mg/250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Doltrax MR 50mg/325mg/250mg Tablet may be needed. Please consult your doctor. Liver: Doltrax MR 50mg/325mg/250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Doltrax MR 50mg/325mg/250mg Tablet may be needed. Please consult your doctor.However, the use of Doltrax MR 50mg/325mg/250mg Tablet is not recommended in patients with severe liver disease and active liver disease.