Alcohol: It is not known whether it is safe to consume alcohol with Ecoflac Plus 0.45%/5% D.N.S. Please consult your doctor. Pregnancy: Ecoflac Plus 0.45%/5% D.N.S may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Breastfeeding: Information regarding the use of Ecoflac Plus 0.45%/5% D.N.S during breastfeeding is not available. Please consult your doctor. Driving: Ecoflac Plus 0.45%/5% D.N.S may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Kidney: Ecoflac Plus 0.45%/5% D.N.S should be used with caution in patients with kidney disease. Dose adjustment of Ecoflac Plus 0.45%/5% D.N.S may be needed. Please consult your doctor. Liver: Ecoflac Plus 0.45%/5% D.N.S is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Ecoflac Plus 0.45%/5% D.N.S may not be needed in these patients. Please consult your doctor.