Alcohol: No interaction found/established Pregnancy: Opennasal Saline Solution may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Breastfeeding: Information regarding the use of Opennasal Saline Solution during breastfeeding is not available. Please consult your doctor. Driving: No interaction found/established Kidney: No interaction found/established Liver: No interaction found/established