Alcohol: It is unsafe to consume alcohol with Tizanac 50 mg/2 mg Tablet. Pregnancy: Tizanac 50 mg/2 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. Breastfeeding: Tizanac 50 mg/2 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Driving: Tizanac 50 mg/2 mg Tablet may cause side effects which could affect your ability to drive.Tizanac 50 mg/2 mg Tablet may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive. Kidney: Tizanac 50 mg/2 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Tizanac 50 mg/2 mg Tablet may be needed. Please consult your doctor. Liver: Tizanac 50 mg/2 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Tizanac 50 mg/2 mg Tablet may be needed. Please consult your doctor.Use of Tizanac 50 mg/2 mg Tablet is not advised in patients with severe liver disease. Liver function tests are recommended before the start of treatment and then on a regular basis as advised.