Alcohol: Tizalide 100mg Tablet may cause excessive drowsiness with alcohol. Pregnancy: Tizalide 100mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Breastfeeding: Tizalide 100mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Driving: Tizalide 100mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Kidney: Tizalide 100mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Tizalide 100mg Tablet may be needed. Please consult your doctor. Liver: Tizalide 100mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Tizalide 100mg Tablet may be needed. Please consult your doctor.