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Bosentan 125 Tablet is a prescription medicine used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It even helps to improve your quality of life, exercising ability and delay in disease progression.Bosentan 125 Tablet should be taken with or without food. This medicine should be used regularly to get the most benefit from it. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.The most common side effects of this medicine include headache, swelling of the legs and ankles, and diarrhea.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Some serious side effects which mean your doctor should know immediately include Anemia (low number of red blood cells) and abnormal liver function such as nausea, vomiting, dark urine, fever, and dark urine. Your doctor might check you for blood tests to check for anemia and liver function.Before taking this medicine, let your doctor know if you have liver dysfunctioning. Inform your doctor if you are pregnant or breastfeeding. Women are suggested to use reliable contraceptive pills to avoid pregnancy and should continue even after one month of stopping the treatment. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

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Alcohol: Bosentan 125 Tablet may cause excessive drowsiness with alcohol. Pregnancy: Bosentan 125 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby. Breastfeeding: Bosentan 125 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Driving: Bosentan 125 Tablet may cause side effects which could affect your ability to drive.As Bosentan 125 Tablet can induce hypotension (decrease of your blood pressure) which can make you feel dizzy and this can affect your ability to drive. Kidney: Bosentan 125 Tablet is safe to use in patients with kidney disease. No dose adjustment of Bosentan 125 Tablet is recommended. Liver: Bosentan 125 Tablet should be used with caution in patients with liver disease. Dose adjustment of Bosentan 125 Tablet may be needed. Please consult your doctor.Use of Bosentan 125 Tablet is not recommended in patients with moderate and severe liver disease.

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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youҀ™re worried about them Common Side Effects : Headache Ankle swelling Edema (swelling) Diarrhea Anemia (low number of red blood cells) Respiratory tract infection