Alcohol: It is not known whether it is safe to consume alcohol with Retromer 400mg Tablet. Please consult your doctor. Pregnancy: Retromer 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Breastfeeding: Retromer 400mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Driving: It is not known whether Retromer 400mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Kidney: Retromer 400mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Retromer 400mg Tablet is recommended.However, regular monitoring of calcium levels is advisable in these patients. Liver: Retromer 400mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Retromer 400mg Tablet may not be needed in these patients. Please consult your doctor.