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Leuprolide 3.75mg Depot One Combipack is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of the uterus grows excessively and causes symptoms like pain, heavy or irregular periods), uterine fibroids and central precocious puberty (very early puberty).Leuprolide 3.75mg Depot One Combipack is given as an injection under the skin by a qualified medical professional.  Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

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Alcohol: Caution is advised when consuming alcohol with Leuprolide 3.75mg Depot One Combipack. Please consult your doctor. Pregnancy: Leuprolide 3.75mg Depot One Combipack is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby. Breastfeeding: Information regarding the use of Leuprolide 3.75mg Depot One Combipack during breastfeeding is not available. Please consult your doctor. Driving: Leuprolide 3.75mg Depot One Combipack may cause side effects which could affect your ability to drive.Do not drive or operate machinery if you experience drowsiness, dizziness or visual disturbances whilst being treated with Leuprolide 3.75mg Depot One Combipack. Kidney: There is limited information available on the use of Leuprolide 3.75mg Depot One Combipack in patients with kidney disease. Please consult your doctor. Liver: There is limited information available on the use of Leuprolide 3.75mg Depot One Combipack in patients with liver disease. Please consult your doctor.

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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youҀ™re worried about them Common Side Effects : Decreased libido Testicular atrophy Increased sweating Fatigue Muscle weakness Erectile dysfunction Hot flashes

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