Alcohol: It is not known whether it is safe to consume alcohol with Karmed Chromium Picolinate 400 mcg Capsule. Please consult your doctor. Pregnancy: Information regarding the use of Karmed Chromium Picolinate 400 mcg Capsule during pregnancy is not available. Please consult your doctor. Breastfeeding: Karmed Chromium Picolinate 400 mcg Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Driving: It is not known whether Karmed Chromium Picolinate 400 mcg Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Kidney: There is limited information available on the use of Karmed Chromium Picolinate 400 mcg Capsule in patients with kidney disease. Please consult your doctor. Liver: There is limited information available on the use of Karmed Chromium Picolinate 400 mcg Capsule in patients with liver disease. Please consult your doctor.