Alcohol: No interaction found/established Pregnancy: Osmofree Solution is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. Breastfeeding: Osmofree Solution is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Driving: No interaction found/established Kidney: No interaction found/established Liver: No interaction found/established