Alcohol: Caution is advised when consuming alcohol with Mefque 250mg Tablet. Please consult your doctor. Pregnancy: Mefque 250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Breastfeeding: Mefque 250mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Driving: Mefque 250mg Tablet may cause side effects which could affect your ability to drive.Mefque 250mg Tablet can cause dizziness, loss of balance and mental problems and this may affect your ability to drive. Kidney: There is limited information available on the use of Mefque 250mg Tablet in patients with kidney disease. Please consult your doctor. Liver: Mefque 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Mefque 250mg Tablet may be needed. Please consult your doctor.Use of Mefque 250mg Tablet is not recommended in patients with severe liver disease.