Alcohol: Caution is advised when consuming alcohol with Lefrin Drop. Please consult your doctor. Pregnancy: Lefrin Drop may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Breastfeeding: Lefrin Drop is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Driving: Lefrin Drop does not usually affect your ability to drive. Kidney: Lefrin Drop should be used with caution in patients with severe kidney disease. Dose adjustment of Lefrin Drop may be needed. Please consult your doctor.Regular monitoring of blood pressure is advised for dose adjustment. Liver: Lefrin Drop should be used with caution in patients with liver disease. Dose adjustment of Lefrin Drop may be needed. Please consult your doctor.