Alcohol: Ceffix O 200mg/200mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Ceffix O 200mg/200mg Tablet may be needed. Please consult your doctor. Pregnancy: Ceffix O 200mg/200mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Ceffix O 200mg/200mg Tablet may be needed. Please consult your doctor.