Alcohol: It is unsafe to consume alcohol with Acefe 200mg Tablet. Pregnancy: Acefe 200mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. Breastfeeding: Information regarding the use of Acefe 200mg Tablet during breastfeeding is not available. Please consult your doctor. Driving: Acefe 200mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Kidney: Acefe 200mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Acefe 200mg Tablet may be needed. Please consult your doctor.Use of Acefe 200mg Tablet is not recommended in patients with severe kidney disease. Liver: Acefe 200mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Acefe 200mg Tablet may be needed. Please consult your doctor.Use of Acefe 200mg Tablet is not recommended in patients with severe liver disease. Regular monitoring of liver function tests is advisable while the patient is taking this medicine.